Frontiers | Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits
K18-hACE2 mouse (JAX™) | Animalab
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia | bioRxiv
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice | Nature
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia | bioRxiv
Interleukin-1RA Mitigates SARS-CoV-2–Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice | Arteriosclerosis, Thrombosis, and Vascular Biology
Viruses | Free Full-Text | Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice
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RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection: Molecular Therapy - Nucleic Acids
Tau (K18) P301L Mutant Pre-formed Fibrils
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice | Nature Communications
JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
Viruses | Free Full-Text | Characterization of Three Variants of SARS-CoV-2 In Vivo Shows Host-Dependent Pathogenicity in Hamsters, While Not in K18-hACE2 Mice
The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus | Journal of Virology
JAX donors contribute $100,000 to new COVID-19 models
Molecules | Free Full-Text | K18- and CAG-hACE2 Transgenic Mouse Models and SARS-CoV-2: Implications for Neurodegeneration Research
Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5–based COVID-19 vaccine | Science Advances
The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus | Journal of Virology
034860 - K18-hACE2 Strain Details
A Mouse Model of SARS-CoV-2 Infection and Pathogenesis - ScienceDirect
JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
Antiviral compound GC-376 shows efficacy against SARS-CoV-2 in vivo
Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5–based COVID-19 vaccine | Science Advances
Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus | Journal of Virology
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia | bioRxiv
Mouse model of fatal COVID-19 developed for vaccine and drug testing
